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INT3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57633

Novus Biologicals, part of Bio-Techne
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NBP2-57633
NBP2-57633-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for INT3 Antibody

Immunocytochemistry/ Immunofluorescence: INT3 Antibody [NBP2-57633]

Immunocytochemistry/ Immunofluorescence: INT3 Antibody [NBP2-57633]

Immunocytochemistry/Immunofluorescence: INT3 Antibody [NBP2-57633] - Staining of human cell line MCF7 shows localization to nucleus & nucleoli.
Immunohistochemistry-Paraffin: INT3 Antibody [NBP2-57633]

Immunohistochemistry-Paraffin: INT3 Antibody [NBP2-57633]

Immunohistochemistry-Paraffin: INT3 Antibody [NBP2-57633] - Staining of human fallopian tube shows strong positivity in glandular cells.
INT3 Antibody

Immunohistochemistry-Paraffin: INT3 Antibody [NBP2-57633] -

Immunohistochemistry-Paraffin: INT3 Antibody [NBP2-57633] - Staining of human skin shows strong nuclear positivity in squamous epithelial cells.

Applications for INT3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100. IHC-P, Retrieval method: HIER pH6.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INT3

INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM]

Alternate Names

C1orf193, C1orf60, chromosome 1 open reading frame 60, DKFZp686E1950, DKFZp686O20115, DKFZp781I1253, FLJ21919, FLJ44849, INT3, integrator complex subunit 3, RP11-216N14.4, Sensor of single-strand DNA complex subunit A, sensor of ssDNA A, Sensor of ssDNA subunit A, SOSS complex subunit A, SOSS-A

Gene Symbol

INTS3

Additional INT3 Products

Product Documents for INT3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for INT3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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