Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37384

Novus Biologicals, part of Bio-Techne
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NBP2-37384
NBP2-37384-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2E10C9

Format

BSA Free

Concentration

1 mg/ml

View all Integrin alpha 2b/CD41 Antibodies »

Product Summary for Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

Immunogen

Purified recombinant fragment of human Integrin alpha 2b/CD41 (AA: 45-149) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

113.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

Western Blot: Integrin alpha 2b/CD41 Antibody (2E10C9)BSA Free [NBP2-37384]

Western Blot: Integrin alpha 2b/CD41 Antibody (2E10C9)BSA Free [NBP2-37384]

Western Blot: Integrin alpha 2b/CD41 Antibody (2E10C9) [NBP2-37384] - Western blot analysis using ITGA2B mAb against HEK293 (1) and ITGA2B (AA: 45-149)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemistry: Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free [NBP2-37384]

Immunohistochemistry: Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free [NBP2-37384]

Immunohistochemistry: Integrin alpha 2b/CD41 Antibody (2E10C9) [NBP2-37384] - Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using ITGA2B mouse mAb with DAB staining.
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free [NBP2-37384]

Flow Cytometry: Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free [NBP2-37384]

Flow Cytometry: Integrin alpha 2b/CD41 Antibody (2E10C9) [NBP2-37384] - Flow cytometric analysis of HL60 cells using ITGA2B mouse mAb (green) and negative control (purple).
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Applications for Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200-1:1000

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2b/CD41

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Alternate Names

CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b

Gene Symbol

ITGA2B

Additional Integrin alpha 2b/CD41 Products

Product Documents for Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2b/CD41 Antibody (2E10C9) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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