Integrin alpha 2b/CD41 Antibody (S01-1C2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20022

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20022-100ul
NBP3-20022-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-1C2

Concentration

0.3 mg/ml

View all Integrin alpha 2b/CD41 Antibodies »

Product Summary for Integrin alpha 2b/CD41 Antibody (S01-1C2)

Immunogen

A synthetic peptide of human Integrin alpha 2b/CD41 (Uniprot # P08514)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

137 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin alpha 2b/CD41 Antibody (S01-1C2)

Western Blot: Integrin alpha 2b/CD41 Antibody (S01-1C2) [NBP3-20022]

Western Blot: Integrin alpha 2b/CD41 Antibody (S01-1C2) [NBP3-20022]

Western Blot: Integrin alpha 2b/CD41 Antibody (S01-1C2) [NBP3-20022] - Western blot detection of Integrin alpha 2b/CD41 in C6, Hela cell lysates using NBP3-20022 (1:1000 diluted). Predicted band size: 113kDa. Observed band size: 137kDa.

Applications for Integrin alpha 2b/CD41 Antibody (S01-1C2)

Application
Recommended Usage

Western Blot

1/2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2b/CD41

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Alternate Names

CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b

Gene Symbol

ITGA2B

Additional Integrin alpha 2b/CD41 Products

Product Documents for Integrin alpha 2b/CD41 Antibody (S01-1C2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2b/CD41 Antibody (S01-1C2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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