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Integrin alpha D/CD11d Antibody (CA11.8H2) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-65292JF646

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Canine

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG1 Clone # CA11.8H2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Affinity purified CD11 antigen from canine spleen

Reactivity Notes

Reacts with Canine.

Specificity

NB100-65292 recognizes the canine CD11d cell surface antigen (the integrin ad sub-unit). The ad integrin is a newly recognized integrin chain that is expressed as a heterodimer with the b2 integrin (CD18). CD11d is expressed by a sub-population of CD8 positive T cells, macrophages and by gd T cells in the splenic red pulp.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Integrin alpha D/CD11d Antibody (CA11.8H2) [Janelia Fluor® 646]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha D/CD11d

Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood

Alternate Names

ADB2, CD11d, Leukointegrin Alpha D

Gene Symbol

ITGAD

Additional Integrin alpha D/CD11d Products

Product Documents for Integrin alpha D/CD11d Antibody (CA11.8H2) [Janelia Fluor® 646]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha D/CD11d Antibody (CA11.8H2) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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