Key Product Details

Species Reactivity

Rat

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OX-62

Concentration

1 mg/ml

View all Integrin alpha E2/Dendritic Cells Antibodies »

Product Specifications

Immunogen

Density gradient enriched PVG rat thoracic duct dendritic cells

Specificity

NB100-65618 recognizes the OX-62 antigen, shown to be rat alpha E2 integrin which is expressed by dendritic cells of dendritic epidermal T cells, intraepithelial lymphocytes in the small intestine and by cells of denritic morphology in lymphoid organs, at sites where gamma delta T cells are present.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha E2/Dendritic Cells Antibody (OX-62)

Flow Cytometry: Integrin alpha E2/Dendritic Cells Antibody (OX-62) - BSA Free [NB100-65618]

Flow Cytometry: Integrin alpha E2/Dendritic Cells Antibody (OX-62) - BSA Free [NB100-65618]

Flow Cytometry: Integrin alpha E2/Dendritic Cells Antibody (OX-62) [NB100-65618] - Rat splenocytes stained with phycoerythrin conjugated Mouse anti Rat OX-62 in red filled, with PE conjugated Mouse IgG1 isotype control blue line.

Applications for Integrin alpha E2/Dendritic Cells Antibody (OX-62)

Application
Recommended Usage

Flow Cytometry

1:50-1:100

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:25-1:100

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha E2/Dendritic Cells

Dendritic cells are potent antigen presenting cells that possess the ability to stimulate naive T cells. They are critical for the induction of T cell responses resulting in cell mediated immunity. Within different tissues, dendritic cells differentiate and become active in the taking up and processing of antigens, and their subsequent presentation on the cell surface linked to major histocompatibility (MHC) molecules. Upon appropriate stimulation, dendritic cells undergo further maturation and migrate to secondary lymphoid tissues where they present Ag to T cells and induce an immune response.

Alternate Names

antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide, CD103, CD103 antigen, HML-1 antigen, HUMINAE, integrin alpha-E, Integrin alpha-IEL, integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alphapolypeptide), MGC141996, Mucosal lymphocyte 1 antigen

Gene Symbol

ITGAE

UniProt

O88341 (Rat)

Additional Integrin alpha E2/Dendritic Cells Products

Product Documents for Integrin alpha E2/Dendritic Cells Antibody (OX-62)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha E2/Dendritic Cells Antibody (OX-62)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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