Integrin beta 2/CD18 Antibody (60.3) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12030

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Product Datasheet / COA

Recombinant Monoclonal Antibody

View Available Conjugates

Conjugate

Catalog #

Alexa Fluor 350

NBP3-12030AF350

Alexa Fluor 405

NBP3-12030AF405

Alexa Fluor 488

NBP3-12030AF488

Alexa Fluor 532

NBP3-12030AF532

Alexa Fluor 594

NBP3-12030AF594

Alexa Fluor 647

NBP3-12030AF647

Alexa Fluor 700

NBP3-12030AF700

Alexa Fluor 750

NBP3-12030AF750

Biotin

NBP3-12030B

CoraFluor 1

NBP3-12030CL1

DyLight 350

NBP3-12030UV

DyLight 405

NBP3-12030V

DyLight 488

NBP3-12030G

DyLight 550

NBP3-12030R

DyLight 594

NBP3-12030DL594

DyLight 650

NBP3-12030C

DyLight 680

NBP3-12030FR

DyLight 755

NBP3-12030IR

FITC

NBP3-12030F

HRP

NBP3-12030H

Janelia Fluor 525

NBP3-12030JF525

Janelia Fluor 549

NBP3-12030JF549

Janelia Fluor 585

NBP3-12030JF585

Janelia Fluor 635

NBP3-12030JF635

Janelia Fluor 646

NBP3-12030JF646

Janelia Fluor 669

NBP3-12030JF669

mFluor Violet 450 SE

NBP3-12030MFV450

mFluor Violet 500 SE

NBP3-12030MFV500

mFluor Violet 610 SE

NBP3-12030MFV610

PerCP

NBP3-12030PCP

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, ELISA, Functional (Inhibition), Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG2a Kappa Clone # 60.3

Format

Azide and BSA Free

Concentration

1 mg/ml

View all Integrin beta 2/CD18 Antibodies »

Product Summary for Integrin beta 2/CD18 Antibody (60.3) - Azide and BSA Free

Immunogen

The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.

Specificity

This antibody binds the Integrin beta 2/CD18 component of the beta-2 integrin family which is expressed by leukocytes and neutrophils.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Applications for Integrin beta 2/CD18 Antibody (60.3) - Azide and BSA Free

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Functional (Inhibition)

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: Integrin beta 2/CD18

CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.

Alternate Names

CD18, ITGB2, LCAMB, LFA-1, LFA-1 beta, MAC-1 beta, MF17, p150,95 beta

Gene Symbol

ITGB2

Additional Integrin beta 2/CD18 Products

Product Documents for Integrin beta 2/CD18 Antibody (60.3) - Azide and BSA Free

Product Datasheets

Download Product Datasheets

COA

Product Specific Notices for Integrin beta 2/CD18 Antibody (60.3) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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