Integrin beta 4/CD104 Antibody (5Z9P3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16446

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16446-100ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 5Z9P3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin beta 4/CD104 Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1604-1822 of human ITGB4 (P16144). SQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTHMDQQFFQT

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin beta 4/CD104 Antibody (5Z9P3)

Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446]

Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446]

Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446] - Western blot analysis of extracts of various cell lines, using Integrin beta 4/CD104 (ITGB4/CD104) Rabbit mAb (NBP3-16446) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446]

Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446]

Western Blot: Integrin beta 4/CD104 Antibody (5Z9P3) [NBP3-16446] - Western blot analysis of extracts of Mouse brain, using Integrin beta 4/CD104 (ITGB4/CD104) Rabbit mAb (NBP3-16446) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 3min.

Applications for Integrin beta 4/CD104 Antibody (5Z9P3)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Integrin beta 4/CD104

Integrin beta 4 is a glycoprotein which associates with the a6 integrin to form the a6/b4 complex. Integrin alpha 6/beta 4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Defects in Integrin beta 4 gene are a cause of epidermolysis bullosa letalis with pyloric atresia (EB PA); also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is characterized by mucocutaneous fragility and gastrointestinal atresia, which most commonly affects the pylorus. Moreover, defects in Integrin beta 4 gene are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). This nonlethal form of junctional epidermolysis bullosa is characterized by life long blistering of the skin, associated with hair and tooth abnormalities.

Alternate Names

CD104, ITGB4

Gene Symbol

ITGB4

Additional Integrin beta 4/CD104 Products

Product Documents for Integrin beta 4/CD104 Antibody (5Z9P3)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin beta 4/CD104 Antibody (5Z9P3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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