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IP3KC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49068

Novus Biologicals, part of Bio-Techne
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NBP2-49068
NBP2-49068-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IP3KC Antibody

Western Blot: IP3KC Antibody [NBP2-49068]

Western Blot: IP3KC Antibody [NBP2-49068]

Western Blot: IP3KC Antibody [NBP2-49068] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251MG sp
Immunocytochemistry/ Immunofluorescence: IP3KC Antibody [NBP2-49068]

Immunocytochemistry/ Immunofluorescence: IP3KC Antibody [NBP2-49068]

Immunocytochemistry/Immunofluorescence: IP3KC Antibody [NBP2-49068] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.
Immunohistochemistry: IP3KC Antibody [NBP2-49068]

Immunohistochemistry: IP3KC Antibody [NBP2-49068]

Immunohistochemistry: IP3KC Antibody [NBP2-49068] - Staining of human testis shows strong nuclear and cytoplasmic positivity in cells in seminiferus ducts.

Applications for IP3KC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IP3KC

Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins(1,4,5)P3 to Ins(1,3,4,5)P4, both of which are modulators of calcium homeostasis. ITPK isoforms include ITPKA (MIM 147521), ITPKB (MIM 147522), and ITPKC, all of which contain a conserved catalytic unit in their C termini, but have unique N-terminal sequences and tissue distributions.[supplied by OMIM]

Alternate Names

inositol 14,5-trisphosphate 3-kinase CIP3K C, inositol-trisphosphate 3-kinase C, InsP 3 kinase C, InsP 3-kinase C, IP3 3-kinase C, IP3-3KC, IP3KCEC 2.7.1.127

Gene Symbol

ITPKC

Additional IP3KC Products

Product Documents for IP3KC Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IP3KC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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