IP3R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83105

Novus Biologicals, part of Bio-Techne
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NBP1-83105
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IP3R1 Antibodies »

Product Summary for IP3R1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IP3R1 Antibody

Western Blot: IP3R1 Antibody [NBP1-83105]

Western Blot: IP3R1 Antibody [NBP1-83105]

Western Blot: IP3R1 Antibody [NBP1-83105] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: U-87 MG
Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105] - Staining of human skin shows no positivity in epidermal cells as expected.
Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP1-83105] - Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.
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Applications for IP3R1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IP3R1

IP3R1 (inositol 1,4,5-triphosphate receptor type 1) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian InsP3R receptors: Insp3R1, Insp3R2, and Insp3R3. Defects in the gene which encodes InsP3R1, ITPR1, are the cause of spinocerebellar ataxia type 15 (SCA15).

Long Name

Inositol 1,4,5-trisphosphate receptor type 1

Alternate Names

InsP3R1, IP3R 1, ITPR1

Gene Symbol

ITPR1

Additional IP3R1 Products

Product Documents for IP3R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IP3R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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