IP3R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22458

Novus Biologicals, part of Bio-Techne
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NBP2-22458
NBP2-22458-0.025ml
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat, Canine

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.3 mg/ml

View all IP3R1 Antibodies »

Product Specifications

Immunogen

Synthetic Peptide: N(1829) K K K D D E V D R D A P S R K K A K E(1848)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IP3R1 Antibody

Immunocytochemistry/ Immunofluorescence: IP3R1 Antibody [NBP2-22458]

Immunocytochemistry/ Immunofluorescence: IP3R1 Antibody [NBP2-22458]

Immunocytochemistry/Immunofluorescence: IP3R1 Antibody [NBP2-22458] - Immunolocalization of IP3 receptor type I in rat cerebellum.

Applications for IP3R1 Antibody

Application
Recommended Usage

Flow Cytometry

3 - 5 ug / 10^6 cells

Immunocytochemistry/ Immunofluorescence

2 ug/ml

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Frozen

1:250

Immunoprecipitation

1:10 - 1:500

Western Blot

1:1000
Application Notes
WB: Detects an approx. 240 kDa protein representing IP3R-I from rat and mouse brain extract.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IP3R1

IP3R1 (inositol 1,4,5-triphosphate receptor type 1) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian InsP3R receptors: Insp3R1, Insp3R2, and Insp3R3. Defects in the gene which encodes InsP3R1, ITPR1, are the cause of spinocerebellar ataxia type 15 (SCA15).

Long Name

Inositol 1,4,5-trisphosphate receptor type 1

Alternate Names

InsP3R1, IP3R 1, ITPR1

Entrez Gene IDs

25262 (Rat)

Gene Symbol

ITPR1

Additional IP3R1 Products

Product Documents for IP3R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IP3R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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