IQCB1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29386

Novus Biologicals, part of Bio-Techne
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NBP3-29386
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IQCB1 Antibodies »

Product Specifications

Immunogen

Between 548 and 598

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IQCB1 Antibody

IQCB1 Antibody

Immunoprecipitation:IQCB1 AntibodyNBP3-29386] -

Immunoprecipitation:IQCB1 AntibodyNBP3-29386] -Detection of human IQCB1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-IQCB1 antibody NBP3-29386 (lot NBP3-29386-1) used for IP at 6 µg per reaction. IQCB1 was also immunoprecipitated by rabbit anti-IQCB1 antibody BL21694. For blotting immunoprecipitated IQCB1, NBP3-29386 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for IQCB1 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate pH 7 -8.

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IQCB1

CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. CEP290 is ubiquitously expressed; strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) , Senior-Loken syndrome type 6 (SLSN6) , Leber congenital amaurosis type 10 (LCA10) and Meckel syndrome type 4 (MKS4) . Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.

Alternate Names

IQ calmodulin-binding motif containing 1, IQ motif containing B1, KIAA0036nephrocystin 5, Nephrocystin-5, NPHP5IQ calmodulin-binding motif-containing protein 1, p53 and DNA damage-regulated IQ motif protein, PIQ, SLSN5

Gene Symbol

IQCB1

Additional IQCB1 Products

Product Documents for IQCB1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IQCB1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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