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IQSEC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81480

Novus Biologicals, part of Bio-Techne
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NBP1-81480
NBP1-81480-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IQSEC1 Antibody

Immunocytochemistry/ Immunofluorescence: IQSEC1 Antibody [NBP1-81480]

Immunocytochemistry/ Immunofluorescence: IQSEC1 Antibody [NBP1-81480]

Immunocytochemistry/Immunofluorescence: IQSEC1 Antibody [NBP1-81480] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoli & vesicles.
Immunohistochemistry-Paraffin: IQSEC1 Antibody [NBP1-81480]

Immunohistochemistry-Paraffin: IQSEC1 Antibody [NBP1-81480]

Immunohistochemistry-Paraffin: IQSEC1 Antibody [NBP1-81480] - Staining of human skin shows strong cytoplasmic positivity in basal cells of squamous epithelium.

Applications for IQSEC1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IQSEC1

In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin

Alternate Names

ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, ARFGEP100, BRAG2, IQ motif and Sec7 domain 1, IQ motif and SEC7 domain-containing protein 1, KIAA0763Brefeldin-resistant Arf-GEF 2 protein

Entrez Gene IDs

9922 (Human)

Gene Symbol

IQSEC1

UniProt

Additional IQSEC1 Products

Product Documents for IQSEC1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IQSEC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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