ITPKB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81589

Novus Biologicals, part of Bio-Techne
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NBP1-81589
NBP1-81589-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ITPKB Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ITPKB Antibody

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589] - Analysis in human cerebral cortex and liver tissues. Corresponding ITPKB RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589]

Immunohistochemistry-Paraffin: ITPKB Antibody [NBP1-81589] - Staining of human cerebral cortex shows strong positivity in astrocytes.
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Applications for ITPKB Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in WB reported in scientific literature (PMID 26642205).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITPKB

ITPKB is encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq]

Alternate Names

EC 2.7.1.127, inositol 14,5-trisphosphate 3-kinase BIP3K, inositol-trisphosphate 3-kinase B, InsP 3-kinase B, IP3 3-kinase B, IP3-3KB, IP3K B, IP3KB, IP3K-B, PIG37, proliferation-inducing protein 37

Gene Symbol

ITPKB

Additional ITPKB Products

Product Documents for ITPKB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ITPKB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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