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ITPR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10355

Novus Biologicals, part of Bio-Techne
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NBP3-10355-100ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for ITPR2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN ITPR2. Peptide sequence FRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQ

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ITPR2 Antibody

Western Blot: ITPR2 Antibody [NBP3-10355]

Western Blot: ITPR2 Antibody [NBP3-10355]

Western Blot: ITPR2 Antibody [NBP3-10355] - Western blot analysis of ITPR2 in Fetal Small Intestine lysates. Antibody dilution at 1.0ug/ml

Applications for ITPR2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITPR2

Inositol 1,4,5-triphosphate (IP3) receptors are a form of ligand-gated ion channels that are activated by cytosolic Ca2+ and IP3. They are localized to intracellular membranes, such as the endoplasmic reticulum, and mediate the mobilization of intracellular Ca2+ stores. IP3 receptors play an important role in intracellular Ca2+ signaling in a variety of cell types. There are three IP3 receptor subtypes; IP3R1, IP3R2 and IP3R3, which exist as homo- and heterotetramers. All subtypes are closely associated with calmodulin and FK506-binding protein and are modulated through phosphorylation by PKA, PKC, PKG and CaMKII.

Long Name

Inositol 1,4,5-trisphosphate receptor type 2

Alternate Names

InsP3R2, IP3R 2

Gene Symbol

ITPR2

Additional ITPR2 Products

Product Documents for ITPR2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ITPR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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