Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Long Name

Junctional Adhesion Molecule B

Alternate Names

CD322, JAM2, JAMB, VE-JAM

Gene Symbol

JAM2

UniProt

P57087

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Product Specific Notices for JAM-B/VE-JAM Antibody (MM0425-4L28) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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JAM-B/VE-JAM Antibody (MM0425-4L28) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11745

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Background: JAM-B/VE-JAM