JMJD1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-38879

Novus Biologicals, part of Bio-Techne
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NB110-38879
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all JMJD1B Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1710 and the C-terminus (residue1761) of human Jumonji Domain Containing 1B using the numbering given in entry NP_057688.2 (GeneID 51780).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JMJD1B Antibody

Western Blot: JMJD1B Antibody [NB110-38879]

Western Blot: JMJD1B Antibody [NB110-38879]

Western Blot: JMJD1B Antibody [NB110-38879] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. NB110-38879 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B).
Immunohistochemistry: JMJD1B Antibody [NB110-38879]

Immunohistochemistry: JMJD1B Antibody [NB110-38879]

Immunohistochemistry: JMJD1B Antibody [NB110-38879] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- JMJD1B used at a dilution of 1:200 (1ug/ml). Detection: DAB

Applications for JMJD1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: JMJD1B

JMJD1B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1B was identified as the 5qNCA gene that lies within a locus on chromosome 5 that is frequently deleted in myeloid leukemias and myelodysplasias. JMJD1B has been demonstrated to have growth suppressive activity and is implicated as a tumor suppressor gene. Alternate names for JMJD1B include JmjC domain-containing histone demethylation protein 2B, jumonji domain-containing protein 1B, nuclear protein 5qNCA, c5orf7, JHDM2B, and KIAA1082.

Long Name

Lysine-specific demethylase 3B

Alternate Names

C5orf7, EC 1.14.11.65, JHDM2B, KDM3B, KIAA1082

Entrez Gene IDs

51780 (Human)

Gene Symbol

KDM3B

UniProt

NP_057688.2 (Human)

Additional JMJD1B Products

Product Documents for JMJD1B Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for JMJD1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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