Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all JMJD1B Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 20 amino acid synthetic peptide from near the center of human JMJD1B. The immunogen is located within amino acids 1050 - 1100 of JMJD1B. Amino Acid Squence: YRLRKSRPRSETEEMGDEE

Specificity

This antibody will not cross-react with JMJD1A or JMJD1C.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JMJD1B Antibody - BSA Free

Western Blot: JMJD1B AntibodyBSA Free [NBP1-77071]

Western Blot: JMJD1B AntibodyBSA Free [NBP1-77071]

Western Blot: JMJD1B Antibody [NBP1-77071] - Rat liver tissue lysate with JMJD1B antibody at (A) 1 and (B) 2 ug/ml.
JMJD1B Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: JMJD1B Antibody - BSA Free [NBP1-77071] -

Immunocytochemistry/ Immunofluorescence: JMJD1B Antibody - BSA Free [NBP1-77071] - Immunofluorescence of JMJD1B in rat liver tissue with JMJD1B antibody at 20 u/mL.
JMJD1B Antibody - BSA Free

Immunohistochemistry: JMJD1B Antibody - BSA Free [NBP1-77071] -

Immunohistochemistry: JMJD1B Antibody - BSA Free [NBP1-77071] - Immunohistochemistry of JMJD1B in rat liver tissue with JMJD1B antibody at 2.5 u/mL.

Applications for JMJD1B Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Reviewed Applications

Read 1 review rated 4 using NBP1-77071 in the following applications:

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JMJD1B

The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist. This antibody will not cross-react with JMJD1A or JMJD1C.

Long Name

Lysine-specific demethylase 3B

Alternate Names

C5orf7, EC 1.14.11.65, JHDM2B, KDM3B, KIAA1082

Entrez Gene IDs

51780 (Human)

Gene Symbol

KDM3B

UniProt

Q7LBC6 (Human)

Additional JMJD1B Products

Product Documents for JMJD1B Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for JMJD1B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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