JNK1/JNK2 Antibody (SR1786)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22653

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22653-100ul
NBP3-22653-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1786

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all JNK1/JNK2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human JNK1/JNK2 (Uniprot #: P45983, P53779)

Specificity

Detects endogenous levels of total JNK1/JNK2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JNK1/JNK2 Antibody (SR1786)

Western Blot: JNK1/JNK2 Antibody (SR1786) [NBP3-22653] -

Western Blot: JNK1/JNK2 Antibody (SR1786) [NBP3-22653] - Western blot analysis using NBP3-22653 in HeLa cell lysate.

Applications for JNK1/JNK2 Antibody (SR1786)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JNK1/JNK2

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

Long Name

C-Jun N-terminal Kinase

Alternate Names

c-Jun N-terminal kinase 1, JNK, JNK1, JNK1A2, JNK21B1/2, JNK-46, JUN N-terminal kinase, MAP kinase 8, mitogen-activated protein kinase 8, PRKM8, SAPK1, SAPK1C, Stress-activated protein kinase 1, stress-activated protein kinase 1c

Gene Symbol

MAPK8

Additional JNK1/JNK2 Products

Product Documents for JNK1/JNK2 Antibody (SR1786)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for JNK1/JNK2 Antibody (SR1786)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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