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JSRP1 Antibody (6A9)

Novus Biologicals, part of Bio-Techne | Catalog # H00126306-M02-100ug

Novus Biologicals, part of Bio-Techne
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H00126306-M02-100ug

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 6A9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

JSRP1 (NP_653217.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQT

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for JSRP1 Antibody (6A9)

Western Blot: JSRP1 Antibody (6A9) [H00126306-M02-100ug]

Western Blot: JSRP1 Antibody (6A9) [H00126306-M02-100ug]

Western Blot: JSRP1 Antibody (6A9) [H00126306-M02-100ug] - Detection against Immunogen (36.74 KDa) .
ELISA: JSRP1 Antibody (6A9) [H00126306-M02-100ug]

ELISA: JSRP1 Antibody (6A9) [H00126306-M02-100ug]

ELISA: JSRP1 Antibody (6A9) [H00126306-M02-100ug] - Detection limit for recombinant GST tagged JSRP1 is 0.03 ng/ml as a capture antibody.

Applications for JSRP1 Antibody (6A9)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: JSRP1

The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR®s) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR®s), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR®s and RyR®s. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.

Alternate Names

FLJ32416, JP45, JP-45homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45, junctional sarcoplasmic reticulum protein 1,2310032K21Rik, Junctional-face membrane protein of 45 kDa homolog, skeletal muscle sarcoplasmic reticulum protein JP-45

Entrez Gene IDs

126306 (Human)

Gene Symbol

JSRP1

OMIM

608743 (Human)

Additional JSRP1 Products

Product Documents for JSRP1 Antibody (6A9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for JSRP1 Antibody (6A9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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