JSRP1 Antibody [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98019PE

Novus Biologicals, part of Bio-Techne
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NBP2-98019PE
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all JSRP1 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human JSRP1 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for JSRP1 Antibody [PE]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: JSRP1

The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR®s) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR®s), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR®s and RyR®s. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.

Alternate Names

FLJ32416, JP45, JP-45homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45, junctional sarcoplasmic reticulum protein 1,2310032K21Rik, Junctional-face membrane protein of 45 kDa homolog, skeletal muscle sarcoplasmic reticulum protein JP-45

Gene Symbol

JSRP1

Additional JSRP1 Products

Product Documents for JSRP1 Antibody [PE]

Product Datasheets

Certificate of Analysis

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Product Specific Notices for JSRP1 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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