JunD [p Ser255] Antibody (SR1628)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21564

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21564-100ul
NBP3-21564-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1628

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all JunD Antibodies »

Product Summary for JunD [p Ser255] Antibody (SR1628)

Immunogen

A synthesized peptide derived from human phospho-JunD [Ser255] (Uniprot #: P17535)

Modification

p Ser 255

Specificity

Detects endogenous levels of phospho-JunD [Ser255]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JunD [p Ser255] Antibody (SR1628)

Western Blot: JunD [p Ser 255] Antibody (SR1628) [NBP3-21564] -

Western Blot: JunD [p Ser 255] Antibody (SR1628) [NBP3-21564] - Western blot analysis using NBP3-21564 in (1) HeLa cell lysate treated with Alkaline Phosphatase; (2) HeLa cell lysate.

Applications for JunD [p Ser255] Antibody (SR1628)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JunD

The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation.

Long Name

JunD Proto-oncogene

Alternate Names

AP-1

Gene Symbol

JUND

Additional JunD Products

Product Documents for JunD [p Ser255] Antibody (SR1628)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for JunD [p Ser255] Antibody (SR1628)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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