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KA1/GRIK4/Glutamate Receptor KA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62686

Novus Biologicals, part of Bio-Techne
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NBP2-62686
NBP2-62686-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LWTLRHSEATEVSVCQEMVTELRSIILCQDSIH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KA1/GRIK4/Glutamate Receptor KA1 Antibody

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686] - Staining of human caudate shows moderate positivity in neuronal projections.
Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686] - Analysis in human cerebral cortex and pancreas tissues using Anti-GRIK4 antibody. Corresponding GRIK4 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686]

Immunohistochemistry-Paraffin: KA1/GRIK4/Glutamate Receptor KA1 Antibody [NBP2-62686] - Staining of human cerebral cortex shows high expression.

Applications for KA1/GRIK4/Glutamate Receptor KA1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KA1/GRIK4

The GRIK4 gene encodes a glutamate receptor KA-1 protein that is 956 amino acids long, 107 kDA and functions in the major excitatory neurotransmitter in the central nervous system (CNS) by activation of ligand-gated ion channels and G protein-coupled membrane receptors. GRIK4 participate in the neuroactive ligand-receptor interaction, glutamatergic synapse, activation of calcium-permeable kainate receptors, and transmission across chemical synapses. It is known to mainly interact with the GRIK2 gene. Researchers have investigated the role of GRIK4 in bipolar disorder, carcinoma, schizophrenia, parkinson's disease, neuronitis and medulloblastoma.

Long Name

Glutamate Receptor KA1

Alternate Names

EAA1, GluK4, GRIK4

Gene Symbol

GRIK4

Additional KA1/GRIK4 Products

Product Documents for KA1/GRIK4/Glutamate Receptor KA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KA1/GRIK4/Glutamate Receptor KA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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