Kallikrein 6/Neurosin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98247

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Kallikrein 6/Neurosin Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Mouse Kallikrein 6/Neurosin (Accession#: NP_035307.2; Met 8-Leu 253)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Kallikrein 6/Neurosin Antibody

Western Blot: Kallikrein 6/Neurosin Antibody [NBP2-98247]

Western Blot: Kallikrein 6/Neurosin Antibody [NBP2-98247]

Western Blot: Kallikrein 6/Neurosin Antibody [NBP2-98247] - Anti-Kallikrein 6/Neurosin rabbit polyclonal antibody at 1:500 dilution. Lane A: Mouse liver Tissue Lysate. Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 27 kDa. Observed band size: 32 kDa

Applications for Kallikrein 6/Neurosin Antibody

Application
Recommended Usage

ELISA

1:25000-1:50000

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Kallikrein 6/Neurosin

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion. It is upregulated in several types of cancers including colon and ovarian cancers.

Alternate Names

KLK6, Neurosin, Protease M, PRSS18, PRSS9, SP59, Zyme

Gene Symbol

KLK6

Additional Kallikrein 6/Neurosin Products

Product Documents for Kallikrein 6/Neurosin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Kallikrein 6/Neurosin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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