Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all KANK2 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 550 and 600 of human KN motif and ankyrin repeat domains 2 (SRC-1 interacting protein) using the numbering given in entry NP_056308.2 (GeneID 25959).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KANK2 Antibody

Western Blot: KANK2 Antibody [NB100-68217]

Western Blot: KANK2 Antibody [NB100-68217]

Western Blot: KANK2 Antibody [NB100-68217] - Detection of Human KANK2/SIP on HeLa whole cell lysate using NB100-68217. KANK2/SIP was also immunoprecipitated by rabbit anti-KANK2/SIP antibody NB100-68218.
Immunohistochemistry: KANK2 Antibody [NB100-68217]

Immunohistochemistry: KANK2 Antibody [NB100-68217]

Immunohistochemistry: KANK2 Antibody [NB100-68217] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- KANK2/SIP used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Applications for KANK2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KANK2

KANK2/SIP was first identified during a genome wide-screen for proteins that interact with the SRC transcriptional coactivator. KANK2/SIP was also identified by domain and phylogenetic analysis to be a member of the KANK ankyrin-repeat domain-containing protein family. KANK related proteins possess a conserved ankyrin-repeat and coiled-coil domain. KANK2, as well as other KANK proteins, appear to play a role in the formation of actin stress fibers.

Alternate Names

ANKRD25, ankyrin repeat domain 25, Ankyrin repeat domain-containing protein 25, DKFZp434N161, FLJ20004, KIAA1518SRC1-interacting protein, kidney ankyrin repeat-containing protein 2, KN motif and ankyrin repeat domain-containing protein 2, KN motif and ankyrin repeat domains 2, Matrix-remodeling-associated protein 3, matrix-remodelling associated 3, MGC119707, MXRA3, SIP, SRC-1 interacting protein, SRC-1-interacting protein

Entrez Gene IDs

25959 (Human)

Gene Symbol

KANK2

UniProt

NP_056308.2 (Human)

Additional KANK2 Products

Product Documents for KANK2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KANK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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