Kappa Light Chain Antibody (HP6053 + L1C1) [DyLight 594]

Validated:

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Monoclonal Mouse IgG1 Kappa/IgG1 Kappa Clone # HP6053 + L1C1

Please see the vial label for concentration. If unlisted please contact technical services.

Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1)

Cell Surface, cytoplasmic and secreted

This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

B-Cell Marker

Monoclonal

Mouse

IgG1 Kappa/IgG1 Kappa

Protein A or G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.