KCC2/SLC12A5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49674

Novus Biologicals, part of Bio-Techne
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NBP2-49674
NBP2-49674-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KCC2/SLC12A5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIHDQSAPSC

Reactivity Notes

Rat (81%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCC2/SLC12A5 Antibody

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674]

Immunohistochemistry-Paraffin: KCC2/SLC12A5 Antibody [NBP2-49674] - Staining in human cerebral cortex and pancreas tissues using anti-SLC12A5 antibody. Corresponding SLC12A5 RNA-seq data are presented for the same tissues.

Applications for KCC2/SLC12A5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCC2/SLC12A5

K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. (provided by RefSeq)

Long Name

K-Cl Cotransporter 2

Alternate Names

SLC12A5

Gene Symbol

SLC12A5

Additional KCC2/SLC12A5 Products

Product Documents for KCC2/SLC12A5 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for KCC2/SLC12A5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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