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KCC4/SLC12A7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85133

Novus Biologicals, part of Bio-Techne
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NBP1-85133
NBP1-85133-25ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AARTQAPPTPDKVQMTWTREKLIAEKYRSRDTSLSGFKDLFSMKPDQSNV

Reactivity Notes

Mouse reactivity reported in (PMID:31911626). Rat (82%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCC4/SLC12A7 Antibody

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133]

Immunohistochemistry-Paraffin: KCC4/SLC12A7 Antibody [NBP1-85133] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Applications for KCC4/SLC12A7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

Reported in PMID (31911626)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCC4/SLC12A7

KCC4 mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inn

Long Name

Potassium/Chloride Transporter KCC4

Alternate Names

SLC12A7

Gene Symbol

SLC12A7

Additional KCC4/SLC12A7 Products

Product Documents for KCC4/SLC12A7 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KCC4/SLC12A7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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