KCNN4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33694

Novus Biologicals, part of Bio-Techne
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NBP2-33694
NBP2-33694-25ul
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KCNN4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (85%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCNN4 Antibody

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694] - Staining of human colon shows strong cytoplasmic/ membranous positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694]

Immunohistochemistry-Paraffin: KCNN4 Antibody [NBP2-33694] - Staining of human prostate shows strong cytoplasmic/ membranous positivity in smooth muscle cells.
View 1 more images

Applications for KCNN4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reactivity reported in (PMID: 25848765)

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCNN4

KCNN4 (Kca3.1) is part of a potentially heterotetrameric voltage independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium activated potassium channel in T lymphocytes.

Long Name

Intermediate conductance calcium-activated potassium channel protein 4

Alternate Names

IKCa1, KCa3.1, KCa4, SK4, SKCa 4, SKCa4

Gene Symbol

KCNN4

UniProt

O15554 (Human)

Additional KCNN4 Products

Product Documents for KCNN4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KCNN4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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