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KCNT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14146

Novus Biologicals, part of Bio-Techne
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NBP2-14146
NBP2-14146-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for KCNT2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: GIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCNT2 Antibody

Immunocytochemistry/ Immunofluorescence: KCNT2 Antibody [NBP2-14146]

Immunocytochemistry/ Immunofluorescence: KCNT2 Antibody [NBP2-14146]

Immunocytochemistry/Immunofluorescence: KCNT2 Antibody [NBP2-14146] - Staining of human cell line SH-SY5Y shows localization to vesicles.
Immunohistochemistry-Paraffin: KCNT2 Antibody [NBP2-14146]

Immunohistochemistry-Paraffin: KCNT2 Antibody [NBP2-14146]

Immunohistochemistry-Paraffin: KCNT2 Antibody [NBP2-14146] - Staining of human stomach, upper shows strong cytoplasmic and nuclear positivity in glandular cells.

Applications for KCNT2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCNT2

FUCNTION: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.; Subcellular location: Cell membrane; Multi-pass membrane protein

Alternate Names

KCa4.2, MGC119610, MGC119611, MGC119612, potassium channel subfamily T member 2, potassium channel, subfamily T, member 2, Sequence like an intermediate conductance potassium channel subunit, SLICKMGC119613, SLO2.1, sodium activated potassium channel, sodium and chloride activated ATP sensitive potassium channel, sodium- and chloride-activated ATP-sensitive potassium channel, Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1, sodium-and chloride-activated ATP-sensitive potassium channel (SLICK)

Gene Symbol

KCNT2

Additional KCNT2 Products

Product Documents for KCNT2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KCNT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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