KDELR1 Antibody (SR2670)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27705

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27705-100ul
NBP3-27705-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2670

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all KDELR1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human KDELR1 (Uniprot #: P24390)

Specificity

Detects endogenous levels of total KDELR1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KDELR1 Antibody (SR2670)

Immunohistochemistry-Paraffin: KDELR1 Antibody (SR2670) [NBP3-27705] -

Immunohistochemistry-Paraffin: KDELR1 Antibody (SR2670) [NBP3-27705] - Immunohistochemical analysis of paraffin-embedded human liver

Western Blot: KDELR1 Antibody (SR2670) [NBP3-27705] -

Western Blot: KDELR1 Antibody (SR2670) [NBP3-27705] - Western blot analysis of HeLa cell lysate.

Applications for KDELR1 Antibody (SR2670)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KDELR1

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq]

Alternate Names

ER lumen protein retaining receptor 1, ERD2, ERD2.1KDEL receptor 1, HDEL, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1, KDEL endoplasmic reticulum protein retention receptor 1, PM23, Putative MAPK-activating protein PM23

Gene Symbol

KDELR1

Additional KDELR1 Products

Product Documents for KDELR1 Antibody (SR2670)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KDELR1 Antibody (SR2670)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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