KDM2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1293

Novus Biologicals, part of Bio-Techne
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NB100-1293
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all KDM2B Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-FGQVEEKLLQKLS corresponding to C-Terminus according to NP_115979.3.

Specificity

This antibody is expected to recognize isoform a (NP_115979.3) only.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for KDM2B Antibody

Immunohistochemistry-Paraffin: KDM2B Antibody [NB100-1293]

Immunohistochemistry-Paraffin: KDM2B Antibody [NB100-1293]

Immunohistochemistry-Paraffin: KDM2B Antibody [NB100-1293] - Staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
KDM2B Antibody

Immunohistochemistry: Goat Polyclonal KDM2B Antibody [NB100-1293] -

Immunohistochemistry: Goat Polyclonal KDM2B Antibody [NB100-1293] - (7µg/ml) staining of paraffin embedded Human Skin. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
KDM2B Antibody

Control: Goat Polyclonal KDM2B Antibody [NB100-1293] -

Control: Goat Polyclonal KDM2B Antibody [NB100-1293] - Negative Control showing staining of paraffin embedded Human Skin, with no primary antibody.

Applications for KDM2B Antibody

Application
Recommended Usage

ELISA

Detection limit 1:32000

Immunohistochemistry-Paraffin

5-7 ug/ml
Application Notes
WB: An anonymous customer has reported bands at approx. 170+90 kDa band in lysates HeLa (calculated MW of 153 kDa band according to NP_115979.3).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: KDM2B

Fbxl10 (PCCX2) encodes a nuclear protein carrying a PHD finger, a CXXC domain, and an acidic region. The CXXC domain was found to be sufficient for binding to DNA. The acidic region exhibits a high transactivation ability, but the full-length protein was inactive due to regions which inhibited the acidic region, including the C-terminal region. PCCX1 is activated by proteolytic cleavage, which removes the C-terminal inhibitory region.

Long Name

Lysine-specific demethylase 2B

Alternate Names

CXXC2, F-box protein FBL10, FBL10, FBXL10, JHDM1B, NDY1, PCCX2, Protein JEMMA

Entrez Gene IDs

84678 (Human)

Gene Symbol

KDM2B

UniProt

Q8NHM5 (Human)

Additional KDM2B Products

Product Documents for KDM2B Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for KDM2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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