Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all KHSRP Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 660 and 710 of human KH-type splicing regulatory protein using the numbering given in entry Q92945.3 (GeneID 8570).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KHSRP Antibody

Immunohistochemistry-Paraffin: KHSRP Antibody [NBP1-18911]

Immunohistochemistry-Paraffin: KHSRP Antibody [NBP1-18911]

Immunohistochemistry-Paraffin: KHSRP Antibody [NBP1-18911] - Human breast carcinoma. Antibody: Affinity purified rabbit anti-KSRP used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunoprecipitation: KHSRP Antibody [NBP1-18911]

Immunoprecipitation: KHSRP Antibody [NBP1-18911]

Immunoprecipitation: KHSRP Antibody [NBP1-18911] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-KSRP antibody used for IP at 3 mcg/mg lysate. KSRP was also immunoprecipitated by rabbit anti-KSRP antibody NBP1-18910, which recognizes an upstream epitope.

Applications for KHSRP Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:2000

Immunohistochemistry-Paraffin

1:500 - 1:2000

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Epitope retrieval with Tris-EDTA pH9.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KHSRP

KH-type splicing regulatory protein (KSRP) contains four K homology RNA-binding domains. KH domains are found in a wide variety of proteins including ribosomal proteins, transcription factors, and mRNA processing proteins. KSRP has been found to promote the degradation of mRNAs that encode proteins involved in proliferation and the inflammatory response. Alternative names for KSRP include Far upstream element-binding protein 2, FUSE-binding protein 2, p75 and FUBP2.

Alternate Names

FBP2far upstream element-binding protein 2, FUBP2p75, FUSE binding protein 2, FUSE-binding protein 2, KH type-splicing regulatory protein, KH-type splicing regulatory protein, KSRPMGC99676

Entrez Gene IDs

8570 (Human)

Gene Symbol

KHSRP

UniProt

Q92945.3 (Human)

Additional KHSRP Products

Product Documents for KHSRP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KHSRP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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