KIF18A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85126

Novus Biologicals, part of Bio-Techne
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NBP1-85126
NBP1-85126-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KIF18A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQND

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (82%). Reactivity reported in scientific literature (PMID: 23435261)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

102 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KIF18A Antibody

Immunocytochemistry/ Immunofluorescence: KIF18A Antibody [NBP1-85126]

Immunocytochemistry/ Immunofluorescence: KIF18A Antibody [NBP1-85126]

Immunocytochemistry/Immunofluorescence: KIF18A Antibody [NBP1-85126] - Staining of human cell line U-2 OS shows localization to cytosol, microtubules & cytokinetic bridge. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126]

Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126]

Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126]

Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126]

Immunohistochemistry-Paraffin: KIF18A Antibody [NBP1-85126] - Staining of human fallopian tube shows strong cytoplasmic positivity in glandular cells.
View 2 more images

Applications for KIF18A Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. IC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KIF18A

The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF18 has been demonstrated to be a microtubule depolymerase essential for chromosome alignment at the spindle equator. Alternate names for KIF18A include kinesin family member 18A, kinesin-like protein KIF18A, and DKFZP434G2226.

Long Name

Kinesin-like protein KIF18A

Alternate Names

MS-KIF18A, OK/SW-cl.108

Entrez Gene IDs

81930 (Human)

Gene Symbol

KIF18A

UniProt

Q8NI77 (Human)

Additional KIF18A Products

Product Documents for KIF18A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KIF18A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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