Kinesin 5A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-5628

Novus Biologicals, part of Bio-Techne
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NB120-5628
NB120-5628-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Bovine

Predicted:

Rat (95%). Backed by our 100% Guarantee.

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Kinesin 5A Antibodies »

Product Specifications

Immunogen

Synthetic Peptide: C(1007) G Y E A E D Q A K L F P L H Q E T A A S(1027)

Localization

Concentrated in the cell body of the neurons, particularly in the perinuclear region.

Specificity

This is specific for kinesin 5A and does not detect other kinesin isotypes.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Kinesin 5A Antibody

Western Blot: Kinesin 5A Antibody [NB120-5628]

Western Blot: Kinesin 5A Antibody [NB120-5628]

Western Blot: Kinesin 5A Antibody [NB120-5628] - Analysis of kinesin 5A on mouse neuronal cell extract.
Western Blot: Kinesin 5A Antibody [NB120-5628]

Western Blot: Kinesin 5A Antibody [NB120-5628]

Western Blot: Kinesin 5A Antibody [NB120-5628] - Analysis of Kinesin 5A on human retinal extract using PA1-642

Applications for Kinesin 5A Antibody

Application
Recommended Usage

Flow Cytometry

3 - 5 ug / 10^6 cells

Immunocytochemistry/ Immunofluorescence

1 - 2 ug/ml

Western Blot

0.5 - 2 ug/ml
Application Notes
WB: Detects an approx. 110 kDa (predicted molecular weight: 117 kDa) representing kinesin 5A from mouse neuronal cell lysate and human retinal extracts.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Kinesin 5A

Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.

Alternate Names

D12S1889, KIF5A variant protein, kinesin family member 5A, kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, kinesin, heavy chain, neuron-specific, MY050, Neuronal kinesin heavy chain, NKHC1, NKHCspastic paraplegia 10 (autosomal dominant), SPG10

Entrez Gene IDs

3798 (Human); 16572 (Mouse)

Gene Symbol

KIF5A

Additional Kinesin 5A Products

Product Documents for Kinesin 5A Antibody

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Product Specific Notices for Kinesin 5A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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