KIR2DL4/CD158d Antibody (mAb33) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50052

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow (Cell Surface), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # mAb33

Format

BSA Free

Concentration

1 mg/ml

View all KIR2DL4/CD158d Antibodies »

Product Specifications

Immunogen

NK3.3 cells and KIR2DL4-Ig fusion protein

Specificity

The mouse monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KIR2DL4/CD158d Antibody (mAb33) - BSA Free

Flow (Cell Surface): KIR2DL4/CD158d Antibody (mAb33) - BSA Free [NBP1-50052]

Flow (Cell Surface): KIR2DL4/CD158d Antibody (mAb33) - BSA Free [NBP1-50052]

Flow (Cell Surface): KIR2DL4/CD158d Antibody (mAb33) [NBP1-50052] - Surface staining of CD158d in human peripheral blood using anti-CD158d (mAB#33) PE. Image using the PE format of this antibody.
Flow Cytometry: KIR2DL4/CD158d Antibody (mAb33) - BSA Free [NBP1-50052]

Flow Cytometry: KIR2DL4/CD158d Antibody (mAb33) - BSA Free [NBP1-50052]

Flow Cytometry: KIR2DL4/CD158d Antibody (mAb33) [NBP1-50052] - Human peripheral blood using anti-CD158d (mAB#33) APC.

Applications for KIR2DL4/CD158d Antibody (mAb33) - BSA Free

Application
Recommended Usage

Flow Cytometry

2-6 ug/ml

Immunocytochemistry/ Immunofluorescence

1:10-1:2000

Immunoprecipitation

1:50
Application Notes
Functional Application: Cytokine secretion studies. This antibody is CyTOF ready.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KIR2DL4/CD158d

CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.

Long Name

Killer Cell Immunoglobulin-like Receptor, Two Domain Long Cytoplasmic Tail, 4

Alternate Names

CD158d

Gene Symbol

KIR2DL4

Additional KIR2DL4/CD158d Products

Product Documents for KIR2DL4/CD158d Antibody (mAb33) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KIR2DL4/CD158d Antibody (mAb33) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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