Kir3.1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32958

Novus Biologicals, part of Bio-Techne
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NBP1-32958
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (99%), Chicken (91%), Guinea Pig (99%), Rat (98%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Kir3.1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Kir3.1. The exact sequence is proprietary.

Localization

Membrane, Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Kir3.1 Antibody

Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958]

Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958]

Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution.

Applications for Kir3.1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Kir3.1

FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.; Subcellular location: Membrane, Multi-pass membrane protein.

Long Name

G protein-activated inward rectifier potassium channel 1

Alternate Names

GIRK-1, GIRK1, KCNJ3

Entrez Gene IDs

3760 (Human)

Gene Symbol

KCNJ3

UniProt

P48549 (Human)

Additional Kir3.1 Products

Product Documents for Kir3.1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Kir3.1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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