Kir3.3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57515

Novus Biologicals, part of Bio-Techne
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NBP2-57515
NBP2-57515-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Kir3.3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RLDAHLYWSIPSRLDEKVEEE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Kir3.3 Antibody

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515]

Immunohistochemistry-Paraffin: Kir3.3 Antibody [NBP2-57515] - Staining in human cerebral cortex and pancreas tissues using anti-KCNJ9 antibody. Corresponding KCNJ9 RNA-seq data are presented for the same tissues.

Applications for Kir3.3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Kir3.3

The Kir3.3 (KCNJ9) encodes for a 393 amino acid long, 44 kDA, G-protein activated inward rectifier potassium channel protein that creates heteromultimeric pore-forming complexes. The Kir3.3 gene has been investigated in generalized epilepsy, meniere's disease, pertussis, lung cancer, schizophrenia, and diabetes mellitus. It interacts with the DRD4, KCNJ6, ADRB2, KCNJ3, and DRD2 genes in potassium transporting pathways (inward and outward), G-Beta gamma signaling, neurotransmitter receptor binding and downward transmission in the postsynaptic cell, and ion currents in synaptic transmission.

Alternate Names

G protein-activated inward rectifier potassium channel 3, G protein-coupled inward rectifier potassium channel, GIRK-3, GIRK3KIR3.3, Inward rectifier K(+) channel Kir3.3, inwardly rectifier K+ channel KIR3.3, Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9, potassium inwardly-rectifying channel, subfamily J, member 9

Gene Symbol

KCNJ9

Additional Kir3.3 Products

Product Documents for Kir3.3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Kir3.3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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