KIR3DL2/CD158k Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-42882

Novus Biologicals, part of Bio-Techne
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NBP2-42882
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KIR3DL2/CD158k Antibodies »

Product Summary for KIR3DL2/CD158k Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KIR3DL2/CD158k. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KIR3DL2/CD158k Antibody

Western Blot: KIR3DL2/CD158k Antibody [NBP2-42882]

Western Blot: KIR3DL2/CD158k Antibody [NBP2-42882]

Western Blot: LOC727787 Antibody [NBP2-42882] - Analysis of 30 ug whole cell lysate. A: A431 B: H1299 C: Hela 10% SDS PAGE diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: KIR3DL2/CD158k Antibody [NBP2-42882]

Immunocytochemistry/ Immunofluorescence: KIR3DL2/CD158k Antibody [NBP2-42882]

Immunocytochemistry/Immunofluorescence: LOC727787 Antibody [NBP2-42882] - Analysis of paraformaldehyde-fixed HeLa, using LOC727787 antibody at 1:200 dilution.

Applications for KIR3DL2/CD158k Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KIR3DL2/CD158k

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. (provided by RefSeq)

Long Name

Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 2

Alternate Names

CD158k, CL-5, NKAT4A, NKAT4B

Gene Symbol

KIR3DL2

Additional KIR3DL2/CD158k Products

Product Documents for KIR3DL2/CD158k Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KIR3DL2/CD158k Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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