Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Gerbil

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2A Clone # S366-60

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Kir6.1 Antibodies »

Product Summary for Kir6.1 Antibody (S366-60) [Biotin]

Immunogen

Fusion protein amino acids 306-424 (Cytoplasmic C-terminus) of rat Kir6.1

Reactivity Notes

Use in Gerbil reported in scientific literature (PMID:31573045).

Localization

Membrane

Specificity

Detects 45kDa.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Kir6.1 Antibody (S366-60) [Biotin]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Kir6.1

The Kir6.1 (KCNJ8) gene is essential in membrane function as it encodes an inward-rectifier potassium channel protein that is 424 amino acids long and has a mass of nearly 48 kDA. Dysfunctions in the Kir6.1 gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). Research is investigating its role in various diseases such as retinitis, hypoxia, pancreatitis, myocardial infarction, spasticity, leiomyoma, acute myocardial infarction, and prinzmetal angina. The Kir6.1 gene plays a significant role in ATP sensitive potassium channels, SIDS susceptibility pathways, dopamine feedback into cAMP pathway, and the CFTR-dependent regulation of ion channels in airway epithelium. It interacts with other genes such as KCNJ2, ABCC8, ABCC9, and KCNJ11.

Long Name

ATP-sensitive inward rectifier potassium channel 8

Alternate Names

KCNJ8, uKATP-1

Gene Symbol

KCNJ8

Additional Kir6.1 Products

Product Documents for Kir6.1 Antibody (S366-60) [Biotin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Kir6.1 Antibody (S366-60) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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