KiSS1R/GPR54 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1927

Novus Biologicals, part of Bio-Techne
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NLS1927
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Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bovine, Goat

Cited:

Porcine

Predicted:

Bat (94%), Monkey (94%), Mouse (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all KiSS1R/GPR54 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human KiSS1R/GPR54.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (89%), Marmoset (89%), Rat (89%), Hamster (89%).

Localization

Cell Membrane

Specificity

Human KiSS1R/GPR54. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MYBBP1A (56%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for KiSS1R/GPR54 Antibody - BSA Free

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1927] - Brain, Amygdala
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1927] - Analysis of anti-KISS1R / GPR54 antibody with brain, neurons and glia at 2.5 ug/ml.
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody - BSA Free [NLS1927]

Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1927] - Analysis of anti-KISS1R / GPR54 antibody with human brain, glioblastoma.
View 2 more images

Applications for KiSS1R/GPR54 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2.5 - 20 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: KiSS1R/GPR54

GPR54 is a Metastin Receptor. Metastin, also known as KiSS-1, is a metastasis suppressor gene. Mutations in GPR54 have been shown to cause autosomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, suggesting that GPR54 is a key regulator for the onset of puberty (Seminara et al. 2003). GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.

Long Name

KISS1 Receptor

Alternate Names

AXOR12, GPR54, Hypogonadotropin-1, Metastin Receptor, OT7T175

Entrez Gene IDs

84634 (Human)

Gene Symbol

KISS1R

Additional KiSS1R/GPR54 Products

Product Documents for KiSS1R/GPR54 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KiSS1R/GPR54 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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