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KLHL12/C3IP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17077

Novus Biologicals, part of Bio-Techne
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NBP2-17077

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for KLHL12/C3IP1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human KLHL12/C3IP1. The exact sequence is proprietary.

Reactivity Notes

Zebrafish (87%), Xenopus laevis (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KLHL12/C3IP1 Antibody

Western Blot: KLHL12/C3IP1 Antibody [NBP2-17077]

Western Blot: KLHL12/C3IP1 Antibody [NBP2-17077]

Western Blot: KLHL12/C3IP1 Antibody [NBP2-17077] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.

Applications for KLHL12/C3IP1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KLHL12/C3IP1

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.

Alternate Names

C3IP1kelch-like protein 12, CUL3-interacting protein 1, DKIR, FLJ27152, kelch-like 12 (Drosophila), kelch-like protein C3IP1

Gene Symbol

KLHL12

UniProt

Additional KLHL12/C3IP1 Products

Product Documents for KLHL12/C3IP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KLHL12/C3IP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.