Klotho Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2432

Novus Biologicals, part of Bio-Techne
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NB100-2432
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Klotho Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KRDDAKYMYYLKK corresponding to internal region according to NP_004786.2, NP_710150.1.

Specificity

This antibody is expected to recognise both reported isoforms (NP_004786.2; NP_710150.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Klotho Antibody

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432] - Staining of Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432] - Staining of Human Breast. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for Klotho Antibody

Application
Recommended Usage

Immunohistochemistry

4 - 6 ug/ml

Immunohistochemistry-Paraffin

4 - 6 ug/ml

Peptide ELISA

Detection limit 1:4000
Application Notes
WB: Preliminary experiments in human brain, duodenum, placenta and prostate lysates gave no specific signal but low background. IHC-P: Human breast shows cytoplasm staining in luminal epithelial cells of ducts, while human placenta shows membranous staining.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Klotho

The Klotho gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (

Alternate Names

KL

Entrez Gene IDs

9365 (Human)

Gene Symbol

KL

UniProt

Q9UEF7

Additional Klotho Products

Product Documents for Klotho Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Klotho Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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