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KSR2 Antibody (1G4)

Novus Biologicals, part of Bio-Techne | Catalog # H00283455-M08

Novus Biologicals, part of Bio-Techne
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H00283455-M08

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1G4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

KSR2 (NP_775869, 411 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PAPPLPPSATPPSPLHPSPQCTRQQKNFNLPASHYYKYKQQFIFPDVVPVPETPTRAPQVILHPVTSNPILEGNPLLQIEVEPTSENEEV

Specificity

KSR2 - kinase suppressor of ras 2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for KSR2 Antibody (1G4)

Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08] - Analysis of KSR2 expression in A-431.
Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08] - Western Blot analysis of KSR2 expression in K-562 ( Cat # L009V1 ).
Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08]

Western Blot: KSR2 Antibody (1G4) [H00283455-M08] - Western blot analysis of KSR2 over-expressed 293 cell line, cotransfected with KSR2 Validated Chimera RNAi or non-transfected control. Blot probed with H00283455-M08. GAPDH (36.1 kDa) used as loading control.

Applications for KSR2 Antibody (1G4)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for RNAi validation and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KSR2

Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediatedsignaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibitingMAP3K3-mediated interleukin-8 production

Alternate Names

FLJ25965, hKSR2, kinase suppressor of ras 2, kinase suppressor of Ras-2

Entrez Gene IDs

283455 (Human)

Gene Symbol

KSR2

Additional KSR2 Products

Product Documents for KSR2 Antibody (1G4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KSR2 Antibody (1G4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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