Kv1.2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10293

Novus Biologicals, part of Bio-Techne
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NBP3-10293-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all Kv1.2 Antibodies »

Product Summary for Kv1.2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human Kv1.2 (NP_004965.1). Peptide sequence AAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGD

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Kv1.2 Antibody

Western Blot: Kv1.2 Antibody [NBP3-10293]

Western Blot: Kv1.2 Antibody [NBP3-10293]

Western Blot: Kv1.2 Antibody [NBP3-10293] - Western blot analysis of Kv1.2 in Human MCF7 Whole Cell. Antibody dilution at 1 ug/mL

Applications for Kv1.2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Kv1.2

KCNA2 (Potassium voltage-gated channel subfamily A member 2) mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. KCNA2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Long Name

Potassium voltage-gated channel subfamily A member 2

Alternate Names

KCNA2, NGK1

Gene Symbol

KCNA2

Additional Kv1.2 Products

Product Documents for Kv1.2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Kv1.2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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