Kv1.3 Antibody (1D8)

Novus Biologicals, part of Bio-Techne | Catalog # H00003738-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Kv1.3 Antibodies »

Product Specifications

Immunogen

KCNA3 (AAH35059, 424 a.a. ~ 523 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV

Specificity

KCNA3 - potassium voltage-gated channel, shaker-related subfamily, member 3

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Kv1.3 Antibody (1D8)

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01] - KCNA3 monoclonal antibody (M01), clone 1D8. Analysis of KCNA3 expression in human liver.
Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01] - KCNA3 monoclonal antibody (M01), clone 1D8 Analysis of KCNA3 expression in Hela S3 NE.
Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01]

Western Blot: Kv1.3 Antibody (1D8) [H00003738-M01] - KCNA3 monoclonal antibody (M01), clone 1D8. Analysis of KCNA3 expression in Jurkat.
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Applications for Kv1.3 Antibody (1D8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Kv1.3

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Long Name

Potassium voltage-gated channel subfamily A member 3

Alternate Names

HGK5, HLK3, HPCN3, KCNA3

Entrez Gene IDs

3738 (Human)

Gene Symbol

KCNA3

OMIM

176263 (Human)

UniProt

AAH35059 (Human)

Additional Kv1.3 Products

Product Documents for Kv1.3 Antibody (1D8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Kv1.3 Antibody (1D8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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