Kv7.4 Antibody (2H6)

Novus Biologicals, part of Bio-Techne | Catalog # H00009132-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 2H6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Kv7.4 Antibodies »

Product Specifications

Immunogen

KCNQ4 (NP_004691, 596 a.a. ~ 695 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD

Specificity

KCNQ4 (2H6)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for Kv7.4 Antibody (2H6)

Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01]

Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01]

Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01] - KCNQ4 monoclonal antibody (M01), clone 2H6 Analysis of KCNQ4 expression in IMR-32.
Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01]

Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01]

Western Blot: Kv7.4 Antibody (2H6) [H00009132-M01] - KCNQ4 monoclonal antibody (M01), clone 2H6. Analysis of KCNQ4 expression in NIH/3T3.
Sandwich ELISA: Kv7.4 Antibody (2H6) [H00009132-M01] - Detection limit for recombinant GST tagged KCNQ4 is approximately 1ng/ml as a capture antibody.

Applications for Kv7.4 Antibody (2H6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Kv7.4

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Potassium voltage-gated channel subfamily KQT member 4

Alternate Names

KCNQ4, KQT-like 4

Entrez Gene IDs

9132 (Human)

Gene Symbol

KCNQ4

OMIM

600101 (Human)

UniProt

NP_004691 (Human)

Additional Kv7.4 Products

Product Documents for Kv7.4 Antibody (2H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Kv7.4 Antibody (2H6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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