Kv7.4 Antibody (S43/6) [DyLight 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12899FR

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP2-12899

Alexa Fluor 405

NBP2-12899AF405

Alexa Fluor 488

NBP2-12899AF488

Alexa Fluor 647

NBP2-12899AF647

Alexa Fluor 700

NBP2-12899AF700

DyLight 350

NBP2-12899UV

DyLight 405

NBP2-12899V

DyLight 488

NBP2-12899G

DyLight 755

NBP2-12899IR

Janelia Fluor 549

NBP2-12899JF549

Janelia Fluor 646

NBP2-12899JF646

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Microarray, Western Blot

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # S43/6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Kv7.4 Antibodies »

Product Specifications

Immunogen

Fusion protein amino acids 2-77 of human KCNQ4

Localization

Plasma Membrane , Basal Cell Membrane

Specificity

Detects approx 77kDa.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Description

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Applications for Kv7.4 Antibody (S43/6) [DyLight 680]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Microarray

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Kv7.4

KCNQ4 is encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Potassium voltage-gated channel subfamily KQT member 4

Alternate Names

KCNQ4, KQT-like 4

Gene Symbol

KCNQ4

Additional Kv7.4 Products

Product Documents for Kv7.4 Antibody (S43/6) [DyLight 680]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Kv7.4 Antibody (S43/6) [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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