Lactoferrin Antibody (LF5-1D2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-67260

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow (Intracellular), Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # LF5-1D2

Format

BSA Free

Concentration

1 mg/ml

View all Lactoferrin Antibodies »

Product Specifications

Immunogen

Human lactoferrin

Specificity

The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Lactoferrin Antibody (LF5-1D2) - BSA Free

Flow Cytometry: Lactoferrin Antibody (LF5-1D2) - BSA Free [NBP2-67260]

Flow Cytometry: Lactoferrin Antibody (LF5-1D2) - BSA Free [NBP2-67260]

Flow Cytometry: Lactoferrin Antibody (LF5-1D2) [NBP2-67260] - Intracellular staining of human peripheral blood cells using anti-lactoferrin (LF5-1D2) purified, GAM-APC.

Applications for Lactoferrin Antibody (LF5-1D2) - BSA Free

Application
Recommended Usage

Flow (Intracellular)

1-4 ug/ml

Flow Cytometry

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Lactoferrin

Lactoferrin is an iron binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion. Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency induced anemia. Lactoferrin has been shown to have a role in the immune system and in early development of the embryo. A specific receptor for lactoferrin binding has been implicated in the human fetal intestine. Early embryonic localisation of lactoferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.

Alternate Names

GIG12, HEL110, HLF2, Kaliocin-1, Lactoferricin, Lactoferroxin, Lactotransferrin, LF, LTF, Talalactoferrin

Gene Symbol

LTF

Additional Lactoferrin Products

Product Documents for Lactoferrin Antibody (LF5-1D2) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Lactoferrin Antibody (LF5-1D2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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