Lactoperoxidase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87716

Novus Biologicals, part of Bio-Techne
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NBP2-87716
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all Lactoperoxidase Antibodies »

Product Summary for Lactoperoxidase Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human Lactoperoxidase. Peptide sequence: ENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Lactoperoxidase Antibody

Western Blot: Lactoperoxidase Antibody [NBP2-87716]

Western Blot: Lactoperoxidase Antibody [NBP2-87716]

Western Blot: Lactoperoxidase Antibody [NBP2-87716] - Host: Rabbit. Target Name: LPO. Sample Tissue: Human OVCAR-3 Whole Cell lysates. Antibody Dilution: 1ug/ml

Applications for Lactoperoxidase Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lactoperoxidase

Lactoperoxidase is an antibacterial agent in cow milk. The heme protein lactoperoxidase (LPO), also referred to as salivary peroxidase (SPO), is an oxidoreductase secreted into milk. LPO belongs to the XPO subfamily of the peroxidase family. It is expressed in mammary and salivary glands, and in the presence of H2O2, LPO acts as a catalyst for the oxidation of many phenols and aromatic amines. It is crucial for protecting the lactating mammary gland and intestinal tract of newborn infants against microorganisms. LPO binds one calcium ion per heterodimer and one heme B (iron-protoporphyrin IX) group covalently per heterodimer. The LPO gene, which spans 28 kb, is similar in gene organization and sequence to the peroxidase genes MPO and EPX, suggesting the possibility that these genes evolved from a common ancestral gene. The LPO and MPO genes are arranged in a tail-to-tail manner on chromosome 17q23.1.

Alternate Names

EC 1.11.1, lactoperoxidase, MGC129990, MGC129991, Salivary peroxidase, SAPX, SPOEC 1.11.1.7

Gene Symbol

LPO

Additional Lactoperoxidase Products

Product Documents for Lactoperoxidase Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Lactoperoxidase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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