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Laforin/EPM2A Antibody (6C6)

Novus Biologicals, part of Bio-Techne | Catalog # H00007957-M02

Novus Biologicals, part of Bio-Techne
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H00007957-M02

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

ELISA, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 6C6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

EPM2A (NP_001018051, 101 a.a. ~ 199 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIV

Specificity

EPM2A - epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Laforin/EPM2A Antibody (6C6)

Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02]

Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02]

Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02] - EPM2A monoclonal antibody (M02), clone 6C6 Analysis of EPM2A expression in PC-12.
Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02]

Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02]

Western Blot: Laforin/EPM2A Antibody (6C6) [H00007957-M02] - Analysis of EPM2A expression in transfected 293T cell line by EPM2A monoclonal antibody (M02), clone 6C6.Lane 1: EPM2A transfected lysate(37.2 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: Laforin/EPM2A Antibody (6C6) [H00007957-M02] - Detection limit for recombinant GST tagged EPM2A is approximately 1ng/ml as a capture antibody.

Applications for Laforin/EPM2A Antibody (6C6)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Laforin/EPM2A

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.

Alternate Names

EPM2A, LAFPTPase, LDE, MELF

Entrez Gene IDs

7957 (Human)

Gene Symbol

EPM2A

OMIM

254780 (Human)

Additional Laforin/EPM2A Products

Product Documents for Laforin/EPM2A Antibody (6C6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Laforin/EPM2A Antibody (6C6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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